Scientific Advisors

Robert P. Doyle
Professor of Chemistry, Syracuse University

Xeragenx_Web_Robert Professor Robert Doyle holds a PhD in Chemistry from Trinity College, Dublin, Ireland (2002). He was a RSC fellow at the Australian National University (2002-2003) and a Rudolph Anderson Foundation fellow (2004) while in the Department of Chemistry at Yale University (2003-2005).

He is currently Professor at Chemistry at Syracuse University and Associate Professor of Medicine at SUNY, Upstate Medical University. He also holds an appointment at the Syracuse Veterans Affairs Medical Center.

Professor Doyle is currently funded by the NIH (NIDDK) and several industrial partners and was named CNY University Technology Educator of the year in 2013. His work focuses in part on drug delivery and targeting utilizing the dietary uptake pathway of vitamin B12 (cobalamin).

Sergey N. Fedosov
Senior Researcher, Department of Molecular Biology & Genetics
Aarhus University, Denmark

Xeragenx_Web_SergeySergey Fedosov received his MSc in Biology with a specialization in Biochemistry from Moscow State University, Russia in 1982. He went on to receive his Ph.D. in Biochemistry from Moscow State University in 1989. Beginning in 1992 and through 2001, Sergey joined Aarhus University, Denmark as a Guest Researcher and held this position in the departments of Chemistry and Molecular Biology. In 2001, he became an associate lecturer in the Department of Molecular Biology and in 2008, was appointed as a Senior Scientist in the Department of Engineering. Sergey is currently a Senior Researcher in the Department of Molecular Biology and Genetics.

Sergey’s sphere of specialization is substantially associated with cobalamin (Cbl, vitamin B12) and its transporting proteins and includes the successful cloning and expression of the recombinant Cbl-transporting proteins (transcobalamin and intrinsic factor) in yeast and plants. He has written and contributed to 72 research and educational publications and is a named inventor on 3 patents worldwide.

His important publications in the field of vitamin B12 include the detailed characterization of cobalamin binding proteins, including intrinsic factor, and their mechanisms of Cbl recognition; the structural features of Cbl-protein complexes; as well as binding kinetics analysis of the cobalamin binding proteins. Sergey’s ongoing research is exploring the multi-parameter diagnostics of B12 deficiency, new derivatives of Cbl, and the improved pathways of dietary Cbl delivery.